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January 19, 2016


Research—AHPND Immunity


From Abstract: Five different Vibrio parahaemolyticus strains (SH8, SH108, SH58, AH5 and GD10) isolated from the hepatopancreas of moribund shrimp at farms in China were identified and found capable of inducing massive mortalities in Penaeus vannamei.  Immersion challenge results with the five strains indicated variable virulence, and only GD10 caused massive sloughing of tubule epithelial cells, the most significant symptom of AHPND.  Differences in immune responses were detected 48 hours post-infection by injection or immersion challenge with V. parahaemolyticus (SH8, SH108 and GD10) isolates.  The results suggested that lysozyme and toll-like receptors serve as crucial molecular markers of innate immunity in shrimp against V. parahaemolyticus infection.  Lysozyme is a vital marker for acute bacterial infection, while toll-like receptors serve as a crucial marker for chronic infection.


Source: Journal of Fish Disease.  Identification and Pathogenicity of Vibrio parahaemolyticus Isolates and Immune Responses of Penaeus (Litopenaeus) Vannamei (Boone).   X.P. Hong, D. Xu, Y. Zhuo, H.Q. Liu and L.Q. Lu (email, Key Laboratory of Aquatic Genetic Resources of the Ministry of Agriculture, Shanghai Ocean University, Shanghai 201306, China.  Published Online on January 13, 2016.

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